Peripheral Neuropathy Causes

Peripheral neuropathy may be either inherited or acquired through disease processes or trauma. In some cases, no cause can be identified and this is termed idiopathic peripheral neuropathy.

  • Road traffic accidents
  • Falls
  • Sports-related injuries
  • Surgical procedures
  • Dislocated bone
  • Fractured bone
  • Repeated stress/ motion
  • Diabetes
  • Shingles (post herpetic neuralgia)
  • Vitamin deficiency, particularly B12 and folate
  • Alcohol consumption
  • Under active thyroid gland (hypothyroidism)
  • Autoimmune diseases, including lupus, rheumatoid arthritis or Guillain-Barre syndrome
  • AIDS, whether from the disease or its treatment, syphilis, and kidney failure
  • Inherited disorders, such as amyloid polyneuropathy or Charcot-Marie-Tooth disease
  • Exposure to toxins, such as heavy metals, gold compounds, lead, arsenic, mercury etc
  • Certain medications like statins, cancer therapy drugs etc.
  • Inflammation of the blood vessels (vasculitis)
  • Chronic liver disease
  • Chronic kidney disease
  • Cancers or tumors
  • Hypertension