Peripheral neuropathy may be either inherited or acquired through disease processes or trauma. In some cases, no cause can be identified and this is termed idiopathic peripheral neuropathy.
- Road traffic accidents
- Falls
- Sports-related injuries
- Surgical procedures
- Dislocated bone
- Fractured bone
- Repeated stress/ motion
- Diabetes
- Shingles (post herpetic neuralgia)
- Vitamin deficiency, particularly B12 and folate
- Alcohol consumption
- Under active thyroid gland (hypothyroidism)
- Autoimmune diseases, including lupus, rheumatoid arthritis or Guillain-Barre syndrome
- AIDS, whether from the disease or its treatment, syphilis, and kidney failure
- Inherited disorders, such as amyloid polyneuropathy or Charcot-Marie-Tooth disease
- Exposure to toxins, such as heavy metals, gold compounds, lead, arsenic, mercury etc
- Certain medications like statins, cancer therapy drugs etc.
- Inflammation of the blood vessels (vasculitis)
- Chronic liver disease
- Chronic kidney disease
- Cancers or tumors
- Hypertension